Stopping Cancer Before It Starts: Cervical Cancer

Jan 5, 2026

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Cervical Cancer

  • In 2025, an estimated 13,820 new cases of invasive cervical cancer will be diagnosed in women in the US.
  • This year, an estimated 4,360 women will die from cervical cancer in the US.
  • Cervical Cancer is most common in women 35-44 years old, average diagnosis is 50. Cervical cancer rates have declined in women ages 20–24 (−11% annually) due to HPV vaccine impact.
  • Incidence has dropped by more than half since the 1970s due to screening and HPV vaccination.
  • A GYN appointment takes about half an hour.

Disparities:

  • Incidence of cervical cancer is 50% higher in American Indian/Alaska Native, 30% higher in Hispanic, and 22% higher in Black women compared to White women.
  • Mortality rates for Black and Native American women are about 65% higher than for White women.

Modifiable Risk Factors include:

  • Persistent infection with high-risk HPV is responsible for almost all cervical cancers.  Early sexual activity and multiple sexual partners increase exposure to HPV.
  • Obesity & physical inactivity
  • Smoking
  • Alcohol use (even moderate intake increases risk)

 

American Cancer Society Recommended Cervical Cancer Screenings:

  • Ages 25–65 – Primary HPV test every 5 years (preferred)
  • If HPV test not available:
    • Co-testing every 5 years OR
    • Pap test alone every 3 years

Stop screening

  • After age 65 if regular screening in past 10 years and no CIN2+ in past 25 years
  • After hysterectomy if cervix is removed and no history of cervical cancer or serious precancer

 

This is part 5 of a series on specific Cancers that have preventive screenings.  Stay tuned to find out more about each of the 6 cancers.

To View All Parts Click Here!

 

Written by: Kelly McCall, Manager Health Intelligence Analytics